As described in our former report (Wang X. et al., 2016), 8 week-old WT and Nrf2-null male mice with ICR background fed 8 weeks of control diet (CD) and HFD were used for experiments. All the mice were pathogen-free. Each group consisted of 10 mice. All of the experimental protocols that involve animals were approved by the Northeast Agricultural University Animal Care and Use Committee prior to the initiation of the study.
