Table 1 presents loci in the human genome where there was suggestion of evidence for linkage to alcohol-related phenotypes in more than one study. Locations were identified within broad areas on chromosomes 1, 2, 4 (two QTLs), 5, 6, 15 and 16. Table 2 lists the mouse QTLs for preference and withdrawal. For mouse preference traits, there were 5 QTLs and for acute or chronic withdrawal, 7 QTLs. The boundaries of the region of probable linkage were established for each human QTL. Synteny maps then allowed for the identification of regions of mouse chromosomes that corresponded to those QTLs. Analogous searches were then performed starting with each mouse QTL region. As a result of these initial steps, two cases of apparent concurrence of QTL signal in both species were identified.
