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Chunk #12 — Statistical Analysis

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Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10.
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Multipoint nonparametric linkage analysis was then performed using the haplotypes based on the SNPs comprising these clusters as unlinked (composite) markers, thus gaining linkage information while avoiding inaccuracies caused by ignoring the tight intermarker LD between the SNPs.