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Chunk #11 — Statistical Analysis

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Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10.
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in the cluster. In the few instances of an obligate recombination among SNPs in a cluster, genotypes for SNPs in the cluster were recoded as missing for the recombinant individuals. Population haplotype frequencies were calculated using the available genotype data and a maximum-likelihood E-M algorithm. No linkage disequilibrium was assumed between the clusters.