used to compare microarray gene expression profiles were considered across our four SILAC protein data sets, only one (NCAM1) was significantly perturbed in both patients analyzed (Supplementary Table 2). Through four independent SILAC experiments, we identified perturbed proteins with corrected P-values <0.05 and >1.2-fold change in SZ hiPSC NPCs (Supplementary Tables 5–8). These data are illustrated in volcano plots representing relative protein levels in our four independent pairwise comparisons: key cytoskeletal remodeling proteins(cofilins (CFL1 and CFL2) and profilins (PFN1 and PFN2)) and oxidative stress proteins (thioredoxin (TXN) and related proteins) have been highlighted (Figure 2a).
