Chunk #77 — Materials and Methods — Gene sets analyzed with MAGENTA — Mitochondria-related gene sets

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Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.

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A set of 16 known nuclear transcriptional regulators of mitochondrial functions was assembled based on the literature [35], [44]–[48] (Table S11). All mitochondria regulators had SNPs in their extended gene boundaries using the DIAGRAM+ meta-analysis.