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Chunk #78 — Materials and Methods — Gene sets analyzed with MAGENTA — Lipid- and lipoprotein-related gene sets

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Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.
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We tested 15 biological processes related to lipid, fatty acid and steroid metabolism defined by the PANTHER classification method (http://www.pantherdb.org/) [42], and 36 gene sets related to lipid, lipoprotein and fatty acid metabolism defined by Gene Ontology [43], which include 7 molecular functions and 29 biological processes. The Gene Ontology gene sets were taken from the Molecular Signatures Database (MsigDB, http://www.broad.mit.edu/gsea/msigdb/collections.jsp).