paperKB
coga / coga-kb
Help
Sign in

Chunk #11 — Methods — Statistics — Genetic model fitting

Source
Role of overlapping genetic and environmental factors in the relationship between early adolescent conduct problems and substance use in young adulthood.
Embedded
yes

Text

phenotype were completely due to genetic variance, we would expect a twin pair correlation of 1.0 for MZ twins and 0.5 for DZ twins. Both MZ and DZ twin pairs share the C influences, so if C were the only source of variance, we would expect a twin pair correlation of 1.0 for both MZ and DZ pairs. E factors are unique for each individual, so if E were the only source of variance, we would expect a twin pair correlation of zero for both MZ and DZ pairs. In reality, phenotypic variance is generally due to a combination of A, C, and E influences and structural equation modelling is used to determine the combination of influences that best matches the observed data.