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Chunk #26 — Discussion

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Neural connectivity in Internet gaming disorder and alcohol use disorder: A resting-state EEG coherence study.
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In the present study, the AUD group tended to show greater coherence in the relatively slow theta band compared to the HCs. Although previous studies have shown that increased theta oscillations may be a neuropathological marker of AUD54, 55, the present results suggest that there were no differences in EEG synchrony between AUD patients and HCs when psychological variables were controlled for. This may be due to the suppression mechanism associated with theta coherence that is shared by alcohol and the investigated psychological variables, including depression56. The psychological comorbidities that affected the EEG data of the AUD patients in the present study may be explained by the findings of a previous study26. We conducted further analyses to clarify this issue. As a result, all groups exhibited positive correlations between theta coherence and depression and between theta coherence and impulsivity. More specifically, scores on the BDI-II were positively correlated with right fronto-central, right fronto-temporal, and right fronto-parietal theta coherence values (P-values < 0.010) while scores on the BIS-11 were positively correlated with right fronto-parietal and right centro-parietal theta coherence values (P-values