Lifetime affective and generalized anxiety predicted incident nonmedical opioid use, and lifetime panic and generalized anxiety disorders predicted incident nonmedical opioid abuse or dependence [32▪▪]. Wave 1 mood and personality disorders predicted incident drug use (cannabis and/or nonmedical use of sedatives and opioids [33]). Lifetime panic attacks, per se, did not predict incident alcohol or drug disorders [34]. Among NESARC respondents aged at least 60, mood and anxiety disorders did not predict incident substance disorders [29]. Wave 1 overweight or obesity predicted incident major depression, but was inversely related to the risk for incident substance use disorders [35].
