Using methods approved by the University of California, San Diego (UCSD) Human Research committee, a questionnaire was distributed to randomly selected 18–25-year-old Anglo and white Hispanic students. The instrument gathered information on demography and substance use and current DSM-IV major psychiatric disorders through questions from the SSAGA (Semi-Structured Assessment for the Genetics of Alcoholism) interview [38–40]. The answers were used to identify right-handed, healthy students who: 1) had experience with alcohol; 2) no history of brain trauma, epilepsy, alcohol or drug dependence; 3) had no current Axis I or II psychiatric disorder; 4) were not pregnant; and 5) had no irremovable body metal.