The Collaborative Study on the Genetics of Alcoholism (COGA) is an ongoing, multisite family study that began in 1989 and is described in detail elsewhere (Agrawal et al., 2023; Dick, Bucholz et al., 2023; Meyers, Brislin et al., 2023). From 2019–2024 COGA studied the adolescent and young adult offspring from these families in a prospective study with multidomain assessments including clinical interview, neurophysiological and neuropsychological measures, and genetic data). A total of 3,715 offspring (14,495 assessments) from families densely affected with AUD and community comparison families who had at least one parent interviewed in an earlier phase of the COGA study, were enrolled between the ages of 12–22. New participants were added as they reached the age of 12. COGA re-assessed participants ~every two years. In the present study sample, we included 837 prospective study participants (53% female) who were 1) between the ages of 12–16 at first EEG assessment, 2) endorsed exposure to at least one traumatic event by Follow-up 3, 3) had genotypic data available, and 4) had 3 or more EEG assessments. Childhood trauma was defined as trauma occurring by age 12 to ensure that traumatic exposure occurred prior to baseline EEG assessment.
