most robust effects observed for individuals with childhood sexual assaultive trauma, a greater dementia risk and an APOEε4 dose. We further hypothesize that changes in neural connectivity associated with childhood trauma will associate with greater PTSD and AUD symptoms and EEG outcomes in young adulthood. We hope that findings will improve understanding of the way ADRD risk factors (genetics, alcohol use, trauma/PTSD, EEGc patterns) typically examined later in life, may manifest earlier in the lifespan. Further, findings may be used to inform novel therapies for cognitive impairments and ultimately may help to prevent the cascading risk for a wide range of health conditions related to childhood trauma.
