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Chunk #33 — Discussion

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Acute alcohol response phenotype in heavy social drinkers is robust and reproducible.
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In sum, despite these potential limitations, the present study effectively demonstrated that HD have a distinct and reproducible pattern of subjective and objective response to an intoxicating dose of alcohol and provide confirmation of prior findings in an independent sample. As several seminal findings in biological and medical sciences have failed to be replicated (Begley and Ellis 2012; Prinz et al. 2011), the importance of direct replication cannot be overstated.