third session administering a subthreshold dose of alcohol to participants of the second sample. While we found no significant order effects in our previous papers, future studies should attempt to characterize acute responses to various doses of alcohol in HD, including those resulting in BrAC below, and even exceeding the legal limit for intoxicated driving. The FH results should be interpreted with some caution, as the criteria for meeting FH+ was, by including secondary relatives, somewhat broader than in studies examining children of alcoholics. However, both FH groups were evenly represented in the two cohorts (Table 1), increasing confidence in our negative findings in HD.
