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Chunk #15 — Methods — Morris water maze spatial and reversal learning in adults — Visual Cue

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Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice.
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Mice were first tested for their ability to find the 12 cm diameter visible platform having a tall cylinder as the visual cue. This was used to identify whether any mice had visual or motor deficits that could prohibit them from learning the hidden platform tasks. Mice were given four trials per day until criterion was achieved. Each mouse was placed in the pool at one of four possible randomly ordered locations, and then given 60 seconds to find the cued visible platform.