Chunk #38 — Online Methods (Limit 3,000 words, at end of manuscript, currently 2,064) — Replication of gene expression prediction models in independent data

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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.

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First, we used data from the Religious Orders Study and Memory and Aging Project (ROSMAP19,20). This study included genotype data and DLPFC RNA-seq data for 451 individuals of European descent (Supplementary Figure 2b).