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Chunk #39 — Online Methods (Limit 3,000 words, at end of manuscript, currently 2,064) — Replication of gene expression prediction models in independent data

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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
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DLPFC GREX was calculated using the CMC DLPFC predictor models. Correlation between RNA-seq expression and CMC DLPFC GREX (“Replication R2 values” or RR2) was used as a measure of predictive accuracy. RR2 was calculated including correction for ten ancestry components, as follows: