phosphatases (Ppp1r12c, Ppp1r13b, Ptpn23). Pathways related to fibrosis contain a set of collagens that are all expressed at lower levels in the binge-drinking animals. Some genes, including Crebbp, Prkcg, Gsk3b, Ppp3r2, Nfkbia, Dusp1 and Calm1, are shared across the different groups of pathways (Table 3).