There were also significant differences in the interaction between alc-PRS and friend support in relation to alcohol use across developmental stages. This interaction between alc-PRS and friend support was significantly associated with alcohol use in middle adulthood (B = −.40, CI [−.56, −.24], SE = .10, β = −.18, p < .001), but not in emerging adulthood or young adulthood. These associations significantly differed between young adults and middle-aged adults (χ2 = 7.05, df = 1, p = .008) and between emerging adults and middle-aged adults (χ2 = 7.37, df = 1, p = .007), but did not significantly differ between emerging adults and young adults (χ2 = .29, df = 1, p = .593). As illustrated in Figure 2, simple slope analysis indicated that alc-PRS was significantly associated with alcohol use among middle-aged AA adults when friend support was low (−1 SD; B = .24, SE = .10, β = .16, p = .018), but not when friend support was high (+1 SD; B = −.18, SE = .09, β = −.13, p = .035). This interaction effect remained