We estimated the chip-heritability of AUDIT at 12.05% (± 1.91%, P = 2.70 × 10−11, GCTA; 8.8% ± 2.50%, LDSC), which is lower than previous chip-heritability estimates based on dichotomized AUDIT data (30% ±12%; Mbarek et al. 2015), and considerably lower than twin based heritabilities of alcohol abuse, dependence and alcoholism (~50%, (Goldman, Oroszi & Ducci 2005; Enoch 2013), as expected (e.g. Plomin, Haworth, Meaburn, Price & Davis 2013).
