The distribution of the AUDIT scores is shown in Figure 1 and Supplementary Table 2. 472 research participants had AUDIT scores > 15, and 127 had scores > 20, with an average AUDIT response of 3.84, (SD= 3.47). The phenotypic correlations between AUDIT and demographic variables measured in the same cohort are shown in the Supplementary Table 4. Age and sex were negatively correlated with AUDIT scores; younger individuals and males showed higher AUDIT scores (r = −0.15, P < 0.0001; r = −0.17, P < 0.0001, respectively). BMI was negatively associated with AUDIT (r = −0.07, P < 0.0001), whereas household income was positively correlated with AUDIT (r = 0.07, P < 0.0001). AUDIT scores were slightly higher in unmarried individuals (r = −0.02, P = 0.013) but we did not observe significant correlations with years of education (r = 0.01, P = 0.085). Measures of alcohol use were positively correlated with AUDIT scores (r = 0.50–0.52, P < 0.0001).
