Chunk #12 — Materials and Methods — Enrichment of Categories of Genes Common to OZALC-NAG and SAGE Studies

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Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways.

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The statistical significance of the number of categories of genes enriched in both the OZALC-NAG and SAGE studies was empirically evaluated by executing ALIGATOR to evaluate the OZALC-NAG study on the subset of categories of genes significantly enriched in the SAGE study.