Chunk #13 — Materials and Methods — Biological Repositories of Expert Knowledge Analyzed

Source

Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways.

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For the current analysis we included Gene Ontology terms [23] (April 2010) and Kyoto Encyclopedia of Genes and Genomes pathways [24] (October 2010) that contain between 3 and 500 genes interrogated by the Illumina 1 M platform. This resulted in a total of 7962 GO terms and 217 KEGG pathways that we refer to as categories of genes.