or a linked gene(s) in the same region also influenced saccharin and quinine intake, such that rats with the high ethanol preference genotype consumed more of both tastants (Terenina-Rigaldie et al. 2003a). A chromosome 4 QTL was also found in a study using the intercross of the selectively bred preferring (P) and non-preferring (NP) rat lines (Carr et al. 1998) and following further exploration, genes in the region including neuropeptide Y (Npy), α-synuclein (Snca), and corticotrophin-releasing hormone receptor 2 (Crhr2) have been suggested as candidates for the linkage signal (Spence et al. 2009).
