The replication study was performed for the EA and AA samples separately. Among the eight SNPs for SI, two, rs7747583 and rs2349433 at RGS17, passed the replication significance threshold (p < 0.05) and were replicated in the EA male sample (Table 4). Among the four SNPs for ND, two passed the replication significance threshold: rs4424567 at FRMD4A was replicated in the EA male sample, and rs848353 at 7q31.1, close to the hypothetical protein-coding genes C7orf66 and LOC154907, was replicated in the AA total sample. One SNP, at the intronic region of EXOC4, could not be genotyped in the replication study.
