Prior studies have compared gene expression between alcoholics and controls using human post mortem brains (Flatscher-Bader et al., 2010; Flatscher-Bader et al., 2005; Iwamoto et al., 2004; Kryger & Wilce, 2010; Lewohl et al., 2000; Liu et al., 2007; Liu et al., 2006; Mayfield et al., 2002; Sokolov et al., 2003; Zhou et al., 2011b). Others have examined brain regions from animal models (Edenberg et al., 2005; Kerns et al., 2005; Kimpel et al., 2007; McBride et al., 2010; Mulligan et al., 2008; Mulligan et al., 2006; Saito et al., 2004; Tabakoff et al., 2008; Wolen et al., 2012; Worst et al., 2005). The human studies have examined superior frontal cortex (Lewohl et al., 2000; Liu et al., 2007; Liu et al., 2006), frontal cortex (Liu et al., 2007), prefrontal cortex (Flatscher-Bader et al., 2005; Iwamoto et al., 2004), temporal cortex (Sokolov et al., 2003), nucleus accumbens and ventral tegmental area (Flatscher-Bader et al., 2010; Flatscher-Bader et al., 2005), basolateral amygdala (Kryger & Wilce, 2010), and hippocampus (Zhou et al., 2011b). These studies have found down-regulation of myelin-related genes (Liu
