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Chunk #5 — INTRODUCTION

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Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation.
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In this paper, we report on our progress in expanding the RefSeq dataset to include more diverse organisms, describe improvements in data access, and provide examples illustrating an increased focus on providing phylogenetically useful datasets as well as functional feature annotation on RefSeq transcript and protein records. We anticipate these efforts and improvements in the RefSeq dataset will continue to contribute to the advancement of medical translational research, agricultural improvements, phylogenetic identification, and evolutionary studies.