We next performed a set of sensitivity analyses by different treatments of the data, as described in Methods, and found the estimates to be quite robust (Table 3). Notably, although analyses suggested that EGOS and NORDiC cases had slightly different ancestry distributions, the results in Table 3 show that our adjustments for ancestry were sufficient to compensate for these differences (Figures S4–S9, Table S5). In addition, we did not observe a significant difference in heritability between the EGOS and NORDiC cases (Table S5).