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Chunk #19 — RESULTS

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Comparison of alcoholism subtypes as moderators of the response to sertraline treatment.
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Cluster analysis (with k=2) resulted in 40 patients being classified as higher risk/severity (Type B) alcoholics and 94 patients being classified as lower risk/severity (Type A) alcoholics. The SCID-derived age of onset of alcohol dependence yielded 46 EOAs and 88 LOAs. Although 80% of the patients classified as LOAs were classified as Type A alcoholics, fewer than half (48%) of the EOAs were classified as Type B alcoholics, resulting in a modest rate of concordance (κ= 0.28), which was significantly lower (p<0.01) than the concordance (κ = 0.72) that was reported by Roache et al. (2008).