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Chunk #36 — Results — Sub-Cellular Localization of FMN2 Protein in Hippocampal Neurons

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Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression.
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We examined the intracellular distribution of FMN2 protein in neurons using immunocytochemical techniques. All hippocampal pyramidal neurons on a culture dish exhibited distinct and fine granular immunoreactivity for FMN2. The cell body itself had the strongest signal (figure 7A). This fine punctate labeling extended into proximal dendrites and could be followed into distal dendrites. In some instances very thin processes, possibly the axons, were also labeled.