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Chunk #58 — Online Methods — Genome-wide survival association study datasets — (4) Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE)

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A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.
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review board (Medical Ethics Committee) of the Erasmus Medical Center and the Netherlands Ministry of Health, Welfare and Sports Participants were screenedfor prevalent dementia in 1990–93 using a three-stage process; those free of dementia remained under surveillance for incident dementia, a determination made using records linkage and assessment at three subsequent re-examinations. We included all prevalent cases and all incident events up to 31st December 2007.