Chunk #75 — Online Methods — Creation of Cell Type-specific ATAC-seq Profiles

Source

Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder.

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For comparing similarity of peaks called between cell types, the Jaccard index was used, defined here as the number of peaks in one cell type overlapping a peak in the other cell type, divided by the union of the peaks in both cell types.