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Chunk #55 — Conclusions

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Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans.
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We have described a large in-depth data set of multitissue human gene expression. We assessed the variability of the transcriptome among individuals in a large number of tissues at a resolution that provides unique insights in to the diversity and regulation of gene expression among tissues. This analysis provides a unified view of genetic effects on gene expression across a broad range of tissue types, most of which have not been studied for eQTLs previously. We look forward to scaling up the resource to create a data set that will transform our understanding of how genetic variability influences different tissues and biological systems and ultimately complex diseases.