Chunk #54 — Gene network inference within individuals using cross-tissue expression variation — GWAS and eQTLs

Source

Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans.

Embedded

yes

Text

the genetic basis of disease in the fuller context of a wide range of human tissues. The GTEx eQTLs may also be useful in highlighting the role of noncoding genes in disease risk and other complex traits (fig. S34). We found that ~13% of candidate genes proposed by GTEx eQTLs, and in LD to genome-wide significant GWAS SNPs, are noncoding genes (table S15).