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Chunk #9 — 3. RESULTS

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Are genetic variants for tobacco smoking associated with cannabis involvement?
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yes

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Table 2 presents association results for the tobacco smoking and cannabis involvement measures. After correction for multiple testing, the data confirmed previously reported associations between rs6265 (BDNF) and smoking initiation and between rs16969968 (CHRNA5), rs1051730 (CHRNA3) and rs1451240 (CHRNB3) with CPD. For cannabis, rs6265 was associated with lifetime cannabis use while rs1451240 was associated with DSM-IV cannabis abuse/dependence.