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Chunk #5 — Methods and Materials — Subjects

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High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk.
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Age of first drink was defined using the Semi-Structured Assessment for the Genetics of Alcoholism question “How old were you the first time you had your very first whole drink?” Peer drinking was defined using the Semi-Structured Assessment for the Genetics of Alcoholism question “When you were 12–17, how many of your best friends used alcohol?” Answers were none, a few, most, or all. For analysis, we divided responses into two categories: most friends drink and most friends do not drink.