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Chunk #36 — 3. Common liability to addiction — 3.2. Mechanisms of variation in CLA — 3.2.2. Ontogenesis of the liability phenotype

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Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective.
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may be combined with augmented access to drugs, decreased perception of danger and societal disapproval, and indeed with ignoring or approval of this behavior as normative—in certain social groups. Regardless of the role of sensitization, the probability of drug use initiation with a certain drug corresponds to its frequency of use in the population and availability. In the CLA theory, sequencing of drug use is thus not denied but is viewed as opportunistic and trivial.