Data show that drug dependence can indeed be located on the same dimension as premorbid (and even pre-drug-use) behaviors that are indicators of a highly heritable latent trait variably referred to as dysregulation, disinhibition, behavior undercontrol or externalizing behavior, including risks for disruptive behavior disorders (Button et al., 2007; Iacono et al., 2008; Krueger et al., 2002, 2007; Tarter et al., 1999, 2003). At least to some degree, the association of antisocial behavior and illicit drug use is due to the illegality and thus antisociality of drug use. This trait, therefore, can be viewed as substantially overlapping with CLA (Iacono et al., 2008; Vanyukov et al., 2003b). From this perspective, drug use and related addiction are facets of a behavioral set involved with societal norms and their violations. Considering the heritability of this behavioral set, variation in the ability to assimilate these norms is to a large degree based on the individual rather than contextual characteristics.
