Table 8 summarizes the meta-analysis results for the 3 datasets with the COPD trait; as with lung cancer, all subjects were smokers and sex, age, and categorical CPD were included as covariates. In these analyses, only locus 1 provides even suggestive evidence for association though it does not survive multiple test correction (uncorrected p = 0.01). The locus 1 odds ratio is 1.12 (1.02–1.23), a point estimate lower than that for CPD (1.33) and lung cancer (1.31) (Figure 7).
