For locus 1 and locus 2 jointly in the model, locus 1 gave p = 2.68×10−13, OR = 1.26 (1.19–1.34) and locus 2 gave p = 0.012, OR = 0.91 (0.85–0.98). In joint analysis of locus 1 and locus 3, locus 1 yields p = 2.24×10−19, OR = 1.39 (1.30–1.50) and locus 3 gives p = 0.0050, OR = 1.11 (1.03–1.19), showing the same change from protective to risk for the minor allele as was observed in the dichotomous CPD analysis. Finally, in the last pairing, locus 1 gives p = 2.66×10−22 OR = 1.33 (1.26–1.41) and locus 4 gives p = 0.028, OR = 1.26 (1.02–1.55).