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Chunk #5 — Methods — Measures — Cross-Sectional Cohort

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Diagnostic Criteria for Identifying Individuals at High Risk of Progression From Mild or Moderate to Severe Alcohol Use Disorder.
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AUD criteria, diagnoses, and several correlates were derived from the Semi-Structured Interview for the Genetics of Alcoholism (SSAGA).21,22 Sociodemographic variables included sex, race and ethnicity, current income, educational attainment, and relationship status. Psychiatric lifetime Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) (DSM-IV)23 diagnoses included major depressive disorder (MDD), antisocial personality disorder (ASPD), and other SUD diagnoses (endorsing ≥2 DSM-5 criteria for cannabis, cocaine, opiate, stimulant, sedative, or other use disorder or DSM-IV nicotine dependence). In addition, several alcohol-related measures were included as correlates in cross-sectional analyses: (1) lifetime endorsement of drinking every day for a week or more, (2) largest number of drinks consumed each day during this period, (3) lifetime endorsement of experiencing blackouts, (4) age at first intoxication, (5) age at regular drinking onset (ie, drinking once per month for 6 months or more), (6) lifetime maximum number of drinks ever consumed in a single 24-hour period, and (7) lifetime endorsement of seeking professional help or engaging in treatment for drinking problems.