fact that we identify independent association for this gene set implicates these genes in schizophrenia pathophysiology and potentially rejuvenates a previous avenue of 5-HT2C ligand therapeutic endeavor in schizophrenia research38. However, we interpret this result with caution given the small size of this gene set and the fact that a number of its genes encode synaptic proteins that are structurally related to other receptor complexes37, not only 5-HT2C.
