Significant main effects of dose and postadministration time (PAT) [F (1,58) = 456.91; F (1,58) = 9.86; respectively, both ps < 0.002], and their interaction, [F (1,58) = 22.03; p < 0.001] emerged in the analysis of BELs. Post-hoc analyses revealed that ethanol levels derived from the 2.0 g/kg dose were significantly higher than those obtained with 0.5 g/kg ethanol, particularly at the later PAT. BELs were similar across age at the lower ethanol dose and at the early PAT associated with the 2.0 g/kg dose. However, BELs induced by 2.0 g/kg were higher in adolescents than in adults at 32.5 min postadministration (p < 0.0001). This ANOVA also yielded a significant dose x age interaction as well as a significant PAT x age interaction [F (1,58) = 8.41; F (1,58) = 5.40; respectively, both ps < 0.05], with the three-way interaction between dose, age and PAT approaching significance, F (1, 58) = 3.56, p = 0.06.
