Similar results were found when analyzing BrELs. The ANOVA indicated significant main effects of dose and PAT [F (1, 58) = 5599.35, F (1, 58) = 15.50; both ps < 0.001], along with significant interactions of dose x PAT [F (1, 58) = 29.11, p < 0.001], PAT X age [F (1, 58) = 6.67, p < 0.05], and dose x PAT x age [F (1, 58) = 7.64, p < 0.01]. Post-hoc tests indicated that animals administered 2.0 g/kg showed greater BrELs than those receiving 0.5 g/kg, particularly during the second time interval (all ps < 0.0001). Also, brain ethanol levels induced by the 2.0 g/kg dose were higher in adolescents than in adults during the second time interval, as indicated by the pertinent post-hoc test (p < 0.0001). The descriptive profile of BECs and BrELs is shown in Fig. 4.
