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Chunk #144 — Quantification and Statistical Analysis — Analysis of unannotated small-molecule screening libraries

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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
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In addition, we performed query analysis on these compounds' signatures to derive their connectivities to Touchstone perturbagens and PCLs. We found that 111 Discovery compounds had strong and selective connections to PCLs (τ >= 98; PCL specificity >= 0.9).