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Chunk #40 — Review — Chromatin accessibility high-throughput sequence data analysis — Detection of enriched regions — ATAC-seq data

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Chromatin accessibility: a window into the genome.
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ATAC-sec peak calling (Step 13) can be performed also by using ZINBA [103]. Alternatively, our group has found that MACS2 and Hotspot [130] perform equally well with ZINBA at identifying accessible locations (unpublished data).