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Chunk #39 — Results — Development of a reference panel to estimate brain cellular population structure

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Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.
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Due to limited availability of brain cell-type-specific transcriptomic data, we compiled reference samples from different sources, including single-population RNA-seq from mice and human (immunopan-purified oligodendrocytes, neurons, astrocytes and microglia, and iPSC-derived neurons and astrocytes).