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Chunk #26 — Materials and Methods — Analysis of eQTL Enrichment

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Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS.
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All analyses have been conducted using all available information (eQTLs for both CEU and YRI samples) and also using only information from the CEU samples. Results are substantially similar, but because most GWAS reported to date have been conducted in samples of recent European descent, and to be conservative, summary figures use only the eQTL information from the CEU samples. We also provide details for some of the key eQTL studies in tabular form (Table 1), where we provide summary information for enrichment studies using CEU+YRI eQTL data and for enrichment studies using only the CEU eQTL data.