Chunk #84 — PART II. CORE QUESTIONS — F. What is the Content of those Responsibilities? Four Issues and Who Should Address Them — Step 1: Clarifying the criteria and roster
In addition to the need for a central source of advice and information, biobanks themselves and networks or consortia of biobanks (such as the eMERGE Network) need the capacity to address issues involving IFs and IRRs and to tailor central advice on criteria for return to the realities of the biobank’s contributor population, roster of studies, degree and type of de-identification, and capacity for recontact. Increasingly we see biobanks and networks creating such a committee. Use of an Informed Cohort Oversight Board (ICOB),47 for example, has been adopted by the Coriell Personalized Medicine Collaborative.106 The eMERGE Network has a Return of Results Oversight Committee.9,107 GENEVA has a Committee on Incidental Findings.108 Mayo Clinic has established a Biospecimen Trust Oversight Group to determine what results to return and the method for doing so.109 Other biobanks and networks may assign consideration of criteria for returnability to their IRB or conceivably their Data Access Committee (DAC). Some biobanks will find it useful to have all three entities, with the IFs/IRRs committee focusing on that issue, the IRB integrating those concerns with broader human
